I haven't experienced this problem before, but lately in chrome my mouse is very terrible in chrome. I have my sensitivity up all the way and the mouse itself is fine, but once a game starts, it's as though the mouse is at the lowest setting. I thought it was originally an issue with my mouse, however when I tried a game in Internet Explorer and Firefox the mouse performs exactly as it should and is just like it always was (and should be). So I'm not sure what's going on. I don't know if it's an issue with my version of chrome or with a recent update to your software. I would say it's chrome but again, the mouse has been absolutely fine other than recently.
I have tried all basic troubleshooting such as restarting my browser and computer.